Spilanthes (Acmella oleracea): The Natural Toothache Plant for Oral Health, Pain Relief, and Immune Boost

on October 15, 2025

Spilanthes (Acmella oleracea): The Buzz Button Herb for Oral Health, Pain Relief, and Immunity

Spilanthes (Acmella oleracea), often called the “toothache plant” or “buzz buttons,” is one of nature’s most intriguing herbs. It produces a powerful tingling and numbing effect when chewed, which has fascinated herbalists, scientists, and culinary experts alike. Beyond its unique sensory experience, this tropical plant offers impressive health benefits ranging from oral care and minor pain relief to immune and digestive support.

Introduction to Spilanthes (Acmella oleracea)

Spilanthes is a flowering herb native to South America and now cultivated in tropical and subtropical regions around the world. Traditionally used by indigenous communities for oral ailments, fevers, and infections, it is gaining renewed scientific interest due to its bioactive compound spilanthol — a natural analgesic and immune-boosting agent. Its flowers, leaves, and stems are edible and often used in herbal teas, tinctures, or even in culinary dishes for their electric, tingling sensation.

Types of Spilanthes

Acmella oleracea – The most common and widely used species, rich in spilanthol and known for its oral health applications.
Spilanthes acmella – A close relative often used interchangeably; recognized in traditional medicine for fever, sore throat, and digestive issues.
Acmella alba – Less common, used in certain traditional remedies and studied for its antimicrobial potential.

Active Compounds and Mechanism

The primary active compound in Spilanthes is spilanthol, an alkylamide responsible for its numbing and salivation-inducing effects. Spilanthol works by stimulating the trigeminal nerve endings in the mouth, causing a tingling sensation and temporary local anesthesia. It also promotes saliva flow, supports digestion, and enhances oral cleansing. Additionally, the plant contains flavonoids, alkaloids, and essential oils that contribute to its antioxidant, antimicrobial, and anti-inflammatory effects.

Top Health Benefits of Spilanthes (Acmella oleracea)

1. Oral Health and Natural Pain Relief

Spilanthes has long been used as a natural remedy for toothaches, gum pain, and oral infections. Its analgesic and antimicrobial effects help reduce inflammation and bacterial growth in the mouth. Chewing fresh flowers or using Spilanthes mouthwash can numb sore gums and reduce oral discomfort.

2. Boosts Immune System

The herb supports the immune system by stimulating the body’s natural defense mechanisms. Traditional healers used Spilanthes to prevent colds and infections, while modern studies suggest it enhances macrophage activity — cells that help fight pathogens.

3. Supports Digestive Health

Spilanthes stimulates saliva and digestive enzyme secretion, which aids in the breakdown of food and promotes better nutrient absorption. It is also used to relieve bloating, flatulence, and mild stomach discomfort.

4. Natural Anti-inflammatory Properties

Thanks to spilanthol and its flavonoids, Spilanthes acts as a natural anti-inflammatory agent. It helps alleviate pain and swelling from minor injuries, arthritis, or skin irritation when applied topically as an infused oil or balm.

5. Skin and Wound Healing

Spilanthes extracts are commonly included in natural skincare formulations. Its antimicrobial and anti-aging properties support skin repair, reduce wrinkles, and help heal minor wounds. It also helps stimulate collagen production and maintain elasticity.

6. Aphrodisiac and Energy Enhancer

In traditional systems, Spilanthes was used to enhance libido, boost energy, and reduce fatigue. Its mild stimulating properties promote circulation and vitality, particularly in male reproductive health.

7. Antioxidant Protection

The herb is rich in antioxidants that protect against oxidative stress and cellular damage. Regular use may contribute to longevity, healthier skin, and overall vitality.

Traditional and Modern Uses

Traditionally, Spilanthes has been used in Amazonian, African, and Indian herbal medicine for toothaches, fever, infections, and wound care. Modern research now confirms many of these uses, especially its analgesic, antimicrobial, and immunomodulatory effects. It is also gaining popularity in the natural wellness and cosmetic industries for its rejuvenating effects.

Health Treatments and Best Practices

1. For Oral Care

Chew a fresh flower or leaf to numb tooth or gum pain.
Use Spilanthes-infused oil as a natural mouth rinse.
Add dried flowers to warm water for herbal mouthwash.

2. For Digestive Support

Drink Spilanthes tea to stimulate appetite and improve digestion.
Combine with herbs like ginger or peppermint for enhanced results.

3. For Immune Boost

Use tinctures or capsules as a daily immune tonic.
Combine with echinacea or elderberry during cold and flu seasons.

4. For Skin and Pain Relief

Apply Spilanthes-infused oil or salve on inflamed skin or sore joints.
Use in anti-aging or collagen-boosting serums.

Health Risks and Possible Side Effects

While generally safe when used in moderation, Spilanthes may cause mild side effects such as:

Excessive mouth tingling or numbness when overused.
Increased salivation or mild irritation in sensitive users.
Possible allergic reactions in people sensitive to Asteraceae family plants.
Pregnant or breastfeeding women should avoid internal use unless directed by a healthcare professional.

Prevention Tips and Safe Usage

Start with small doses when trying Spilanthes for the first time.
Use reputable organic sources or grow your own without pesticides.
Consult your healthcare provider if you have dental, digestive, or immune disorders.
Store dried Spilanthes flowers in a cool, dry place to preserve spilanthol potency.

Emerging Science and Research Insights

Recent research into Spilanthes highlights its potential in developing natural anesthetic, antimicrobial, and anti-aging formulations. Scientists are investigating how spilanthol could be used as a safer alternative to synthetic numbing agents in dentistry. Additionally, studies point to its antioxidant and collagen-stimulating properties as valuable tools in skincare and regenerative medicine.

How to Use Spilanthes at Home?

Tea: Steep 1 teaspoon of dried Spilanthes flowers in hot water for 10 minutes.
Tincture: Take 10–20 drops in water or juice daily for immune and digestive support.
Oil infusion: Soak fresh flowers in olive or coconut oil for topical applications.
Chewing: Simply chew a flower for instant oral pain relief.

Final Thoughts

Spilanthes (Acmella oleracea) truly stands out as one of nature’s remarkable herbal wonders. From its unmistakable “buzzing” sensation to its therapeutic effects on oral health, digestion, and immunity, it offers a holistic approach to wellness. Whether enjoyed as a tea, tincture, or topical oil, Spilanthes is a valuable addition to any herbal wellness routine. With ongoing research into its active compound spilanthol, the future looks promising for this electrifying herb.